Preheat oven to 375°F (190°C).
Line a baking sheet with parchment paper or lightly grease it.
In a mixing bowl, combine mayonnaise, Parmesan cheese, Ranch seasoning mix, garlic powder, and onion powder until smooth.
Coat each chicken tender in the mayo mixture, then dredge in crushed Ritz crackers, pressing to ensure coating sticks.
Arrange chicken tenders on the prepared baking sheet, spacing them out for even cooking.
Bake for 20-25 minutes, or until golden and cooked through (internal temperature of 165°F).
Allow to cool slightly before serving. Enjoy with your favorite dipping sauce!