Looking for a bold, meaty, and cheesy handheld snack that brings all the flavor of your favorite Italian sub—without bread, sugar, or unnecessary carbs? These Keto Italian Sub Roll-Ups are exactly what you need. With their soft lettuce wrap base, rich deli meat layer, and signature creamy ranch finish, this low-carb version delivers all the richness of classic subs—in a keto-approved, gluten-free format.
Perfect for meal prep , keto-friendly snacks , or when you’re craving something hearty but staying in ketosis, these roll-ups use simple ingredients like salami, mozzarella, and fresh herbs to bring bold Mediterranean flavor into your kitchen. Whether you’re doing strict ketosis , following a low-carb lifestyle , or simply love savory wraps with depth and crunch, these keto Italian sub roll-ups will quickly become a go-to dish in your weekly rotation.
In this article, we’ll walk you through how to make these perfect keto Italian sub roll-ups from scratch , explore ingredient substitutions, offer serving ideas, and answer your most common questions. Let’s dive into the world of soft, crunchy, herb-infused bliss!
Why You’ll Love These Keto Italian Sub Roll-Ups
These aren’t just any old lettuce wraps—they’re a savory-meaty, melt-in-your-mouth delight made with real ingredients that bring bold texture and taste together beautifully—in under 15 minutes!
Here’s why they stand out:
- 🥓 Bold deli meat flavor : Made with salami, ham, or turkey for natural savoriness.
- 🧀 Cheesy richness : Melted mozzarella or provolone adds stretch and creaminess.
- 🌿 Fresh herb seasoning : Oregano, basil, and garlic elevate the flavor without carb overload.
- 🥗 Low-carb wrap option : Uses large lettuce leaves or collard greens for no-gluten crunch.
- 🥣 Easy to make : Just layer, roll, and slice—no cooking required!
- ⏱️ Ready in under 10–12 minutes
- 🧁 Great for batch prep or freezer storage
- 🧼 Minimal cleanup : One bowl = zero mess!
Whether you’re making them for yourself after work, packing for lunch, or sharing at a weekend gathering, these roll-ups will quickly become a go-to handheld snack or breakfast item.
Ingredients You’ll Need
For the Filling:
- 4 oz sliced salami or pepperoni
- 4 oz sliced ham or turkey breast
- 4 oz sliced provolone or mozzarella cheese
- 1 tbsp keto ranch dressing or Greek yogurt-based spread
- 1 tsp dried Italian seasoning (oregano, basil, thyme)
- Crushed red pepper flakes (optional for heat lovers)
Optional: Add chopped olives, sun-dried tomatoes, or fresh spinach for extra flavor.
Final Assembly:
- 6–8 large lettuce leaves (like romaine or butter lettuce) or collard green wraps
- A few drops of olive oil or balsamic glaze for brightness
- Fresh basil or parsley for garnish
Tip: Use pickled banana peppers or roasted red peppers for extra zing.
Step-by-Step Instructions
Step 1: Prep Your Meats and Cheese
Lay out your deli meats and cheese slices on a clean surface.
If desired, layer meats and cheeses together for deeper flavor contrast.
Pro Tip: Choose nitrate-free, minimally processed deli meats for best quality.
Step 2: Layer Toppings on Greens
Place one lettuce leaf or collard green flat on a cutting board.
Smear lightly with keto ranch or Greek yogurt.
Add:
- Deli meat slices
- Cheese layer
- Optional: Olives, peppers, or spinach
Step 3: Roll Into Bite-Sized Treats
Starting from the bottom, gently roll the lettuce tightly around the filling.
Press firmly as you roll to keep it intact.
Secure with a toothpick if needed.
Step 4: Slice and Chill (Optional)
For cleaner presentation, chill the roll-ups in the fridge for 10–15 minutes .
Then slice each roll-up into bite-sized pieces (about 1-inch thick ) for appetizer-style servings.
Step 5: Garnish and Serve!
Once chilled, top with:
- Extra ranch or chipotle mayo drizzle
- Fresh herbs or edible gold dust
- Pickled vegetables or fermented kraut for tangy balance
Serve cold or warm with:
- Guacamole or salsa verde
- As part of a keto charcuterie board
- Over cauliflower rice for full meal upgrade
- In a wrap for double-layered handheld eats
Enjoy every soft, cheesy bite of your Keto Italian Sub Roll-Ups !
Nutritional Information (Per Serving – Makes 4 Servings / ~8 bites)
| Nutrient | Amount |
|---|---|
| Calories | ~150 kcal |
| Total Fat | ~10 g |
| Saturated Fat | ~4 g |
| Cholesterol | ~40 mg |
| Sodium | ~400 mg |
| Total Carbs | ~4 g |
| Dietary Fiber | ~1 g |
| Net Carbs | ~3 g |
| Protein | ~12 g |
Note: Values may vary based on exact measurements and optional add-ins.
Tips for the Best Italian Sub Roll-Ups
- Use quality deli meats and cheese – Ensures better binding and deeper flavor.
- Don’t skip chilling time – Keeps everything intact and prevents crumbling during slicing.
- Layer flavors early and late – Helps build complex taste during cooling and finishing.
- Make ahead and store separately – Keeps best refrigerated in an airtight container.
- Double the batch for future meals – Great for freezing and reheating later.
Variations & Customizations
Want to switch things up? Try these tasty variations:
Chicken Caesar Style
Replace Italian meats with grilled chicken and Caesar dressing for lighter contrast.
No-Bake Energy Bites
Chill the mixture and roll into balls for grab-and-go snacks.
Vegan Option
Use marinated tofu or vegan deli slices with plant-based cheese and ranch.
Spicy Kick
Add jalapeños or drizzle with sriracha for fiery contrast.
Philly Cheesesteak Version
Replace meats with sautéed steak strips and mushrooms for American flair.
Frequently Asked Questions (FAQ)
Are these truly keto-friendly?
Yes! With only ~3g net carbs per serving , it fits perfectly within a ketogenic lifestyle.
Can I use regular flour tortillas or sandwich bread?
Not recommended—standard flour tortillas and bread are high in carbs. Stick with lettuce wraps or collard green rolls for keto compliance.
How do I store leftover roll-ups?
Store cooled portions in an airtight container in the fridge for up to 3 days . Rehydrate with a splash of olive oil or lemon juice before serving.
What kind of lettuce works best?
Butter lettuce or large romaine leaves give the best structure and flavor contrast.
Can I bake instead of chill?
Yes! Wrap in parchment paper and lightly pan-fry or bake for golden crunch.
Why This Recipe Works So Well
These Keto Italian Sub Roll-Ups work because of their perfect balance of textures and bold flavors:
- The meats give body and protein power , soaking up seasonings naturally.
- The lettuce adds freshness and crunch , balancing the richness without heaviness.
- And the cheese melts into a silky finish , completing the American-Italian fusion experience.
It’s the kind of dish that makes eating clean feel indulgent—because it tastes so good.
Serving Suggestions
Looking for creative ways to serve your keto roll-ups beyond just a plate? Here are some ideas:
In Lunchboxes
Pack with veggies, pickles, or cheese for a balanced keto lunch.
At a Kids’ Party
Cut into mini cubes and arrange on a platter with toothpicks for appetizer-style servings.
With Dipping Sauces
Try tzatziki, chipotle mayo, or lime-garlic aioli for extra flair.
Gift-Worthy Packaging
Wrap individual pieces in parchment paper and tie with twine for thoughtful homemade gifts.
Over Greens
Top arugula or spinach with warm roll-up slices and olive oil vinaigrette for fusion flair.
Health Benefits of Key Ingredients
Let’s take a quick look at the health benefits of what makes this dish special:
Salami / Turkey / Mozzarella
High in B vitamins and lean protein—supports muscle repair and energy levels.
Collagen-Rich Pork Rinds / Cheese
Rich in calcium and healthy fats—great for digestion and satiety.
Garlic / Herbs
Natural anti-inflammatory compounds—boosts immunity and heart health.
Even though this is a snack, it’s packed with nutrients that make it more than just a treat—it’s a smart addition to your balanced lifestyle when enjoyed mindfully.
Final Thoughts: A Must-Try Treat for Sandwich Lovers
These Keto Italian Sub Roll-Ups prove that going low-carb doesn’t mean missing out on bold, comforting global flavors. With its soft meat base, crunchy wrap, and signature herb finish, it’s the kind of dish that turns a simple sandwich into something magical—even without bread or sugary sauces.
Whether you’re new to keto meal prep, looking for a fast lunch idea, or want to impress with homemade flair, these roll-ups deserve a spot in your kitchen. They’re easy to make, customizable, and loved by kids and adults alike.
So go ahead—whip up a batch, share them with friends, or savor them solo. Either way, you’re treating yourself to something worth celebrating.
Print
Keto Italian Sub Roll-Up – Savory, Cheesy & Perfectly Low-Carb!
- Total Time: 35 mins
Description
A savory, cheesy twist on the classic sub — these keto roll-ups are packed with bold Italian flavors like pepperoni, salami, mozzarella, and zesty seasonings. Perfect for meal prep, quick snacks, or low-carb entertaining!
Ingredients
For the Spread:
8 oz cream cheese, softened
2 tbsp sour cream or Greek yogurt (full-fat)
1 tsp garlic powder
½ tsp dried oregano
½ tsp dried basil
¼ tsp red pepper flakes (optional, for heat)
Salt and pepper to taste
For the Fillings:
¼ cup thinly sliced pepperoni
¼ cup sliced salami or turkey deli meat
¼ cup shredded mozzarella cheese
2 tbsp sliced sun-dried tomatoes (oil-packed, drained)
2 tbsp sliced banana peppers or chopped pickled jalapeños
1 tbsp chopped fresh basil or parsley
1 tbsp olive oil or balsamic glaze (for drizzle)
For Wrapping:
Large lettuce leaves (butter lettuce, romaine, or collard greens for wrap option)
OR use thin slices of zucchini or cucumber for a grain-free roll-up base
OR keto tortillas or almond flour flatbread for a handheld version
FOR KETO VERSION:
Use low-carb meats , no-sugar-added sun-dried tomatoes , and full-fat dairy . For vegan version, use nut-based cream cheese and plant-based deli meats .
Instructions
Make the Creamy Spread:
In a bowl, beat cream cheese , sour cream , garlic powder , oregano , basil , red pepper flakes , salt, and pepper until light and fluffy.
Tip: Chill for 10–15 minutes to firm up for easier spreading.
Layer the Roll-Ups:
Lay out your choice of wrap: lettuce leaves , zucchini slices , or keto tortillas .
Spread a thick layer of the seasoned cream cheese mixture down the center.
Layer on pepperoni , salami , mozzarella , sun-dried tomatoes , banana peppers , and fresh basil .
Roll & Slice:
Tightly roll up each wrap like a burrito, tucking in the sides as you go.
Wrap in plastic wrap and chill for 15–20 minutes to firm up.
Once set, slice into pinwheels or enjoy whole as handheld wraps.
- Prep Time: 15 mins
- Cook Time: 20 mins
Nutrition
- Serving Size: 6–8
- Calories: 180–200
- Fat: 14g
- Carbohydrates: 3g
- Protein: 10g